ShieldArgent on a bend Azure, between a sprig of long leaf pine with cone Proper and a wildcat rampant Gules; two fleurs-de-lis paleways of the field.
CrestThat for the regiments and separate battalions of the Army Reserve: On a wreath of the colors Argent and Azure the Lexington Minute Man Proper. The statue of the Minute Man, Captain John Parker (H.H. Kitson, sculptor), stands on the Common in Lexington, Massachusetts.
MottoEN AVANT (Forward).
ShieldThe blue bend denotes Infantry, the pine cone proper denoting the home of the regiment - North Carolina - "The Land of the Long Leaf Pine." In base is the 81st Division Wild Cat. The bend is charged with two fleurs-de-lis Argent, denoting the Meuse-Argonne operations and the Lorraine Sector.
CrestThe crest is that of the United States Army Reserve.
The coat of arms was originally approved for the 321st Infantry Regiment on 2 July 1924. It was redesignated for the 321st Regiment on 10 August 1960.