Argent, a cross of four ermine spots Proper.
That for the regiments and separate battalions of the Army Reserve: On a wreath of the colors Argent and Sable the Lexington Minute Man Proper. The statue of the Minute Man, Captain John Parker (H.H. Kitson, sculptor), stands on the Common in Lexington, Massachusetts.
PARATUS ET VIGILANS (Ready and Alert).
The shield is white for Infantry. The ermine spots represent fur. The fur trade along the Columbia River, to which section the 381st Infantry was originally allocated, attracted the settlers to Oregon and Washington.
The coat of arms was originally approved for the 381st Regiment Infantry, Organized Reserves on 5 Mar 1927. It was amended to withdraw "Organized Reserves" from the designation and to delete the Organized Reserves' crest from the coat of arms on 24 Sep 1959. The coat of arms was amended to reinstate the crest of the Army Reserve and revise the symbolism of the design on 3 Aug 1970. On 28 Oct 1993 the coat of arms was redesignated for the 381st Regiment with the symbolism revised.