A gold color metal and enamel device 1 1/8 inches (2.86 cm) in height overall consisting of a red Greek cross crested by a gold heraldic rose all within a maroon scroll lined white. The scroll, horizontal across base, loops inwardly and "S" curves to the terminals of the lateral arms, reverses and terminates at the rose, and bears the inscription on the lower left "STUDY," across the base "HEAL," and on the lower right "TEACH," all in gold.
Maroon and white are the colors for the Army Medical Department. The heraldic rose, suggested by the double rose of the royal badge of England, designates the unit's service in that country during World War II. The red cross is symbolic of aid, assistance and protection from disease.
The distinctive unit insignia was originally approved for the 452d General Hospital on 24 March 1970. It was redesignated for the 452d Combat Support Hospital with the description revised on 6 July 1994.